Pressure Natriuresis and Autoregulation of Inner Medullary Blood Flow in Canine Kidney
نویسندگان
چکیده
منابع مشابه
Pressure natriuresis and autoregulation of inner medullary blood flow in canine kidney.
We have evaluated the responses to changes in arterial pressure on regional blood flows in the renal medulla and sodium excretion simultaneously in denervated kidneys of six anesthetized sodium-replete dogs. Renal regional blood flow responses were determined using laser-Doppler needle flow probes and whole-kidney blood flow was assessed using an electromagnetic flow probe. The responses to ste...
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Recent studies have demonstrated that inhibition of renal medullary heme oxygenase (HO) activity and carbon monoxide (CO) significantly decreases renal medullary blood flow and sodium excretion. Given the crucial role of renal medullary blood flow in the control of pressure natriuresis, the present study was designed to determine whether renal medullary HO activity and resulting CO production p...
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Renal dysfunction has long been a recognized feature of essential hypertension as first suggested by Dr Richard Bright’s mid-19th century observations of small, shrunken, scarred kidneys associated with cardiac hypertrophy and the seminal studies in the 1930s by Dr Harry Goldblatt directly linking the kidney to chronic hypertension. Attention was originally and appropriately focused on the rena...
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ژورنال
عنوان ژورنال: Hypertension
سال: 1997
ISSN: 0194-911X,1524-4563
DOI: 10.1161/01.hyp.29.1.210